Loxapine is an antipsychotic commonly used to treat schizophrenia. Here are some things you may not have known about Loxapine:
Generic Name: Loxapine
Brand Name(s): Adasuve
Pronunciation: LOX a peen
About this drug:
Loxapine is an antipsychotic used to treat schizophrenia.
Dentistry-related tidbits:
Loxapine may cause xerostomia, thrombocytopenia, and stomatitis.
Loxapine may also cause a condition called dysgeusia that causes a foul, rancid, salty, or metallic taste in the mouth. This condition may be accompanied by burning mouth syndrome.
Articaine, Bupivacaine, Lidocaine, Mepivacaine, and Ropivacaine local anesthetics can also cause severe hypotension when combined with Loxapine.
Propofol combined with Loxapine can increase the risk of CNS & respiratory depression, diminished psychomotor function, and severe hypotension.
Common narcotics, benzodiazepines, muscle relaxants, and anticonvulsants can cause CNS depression, diminished psychomotor function, and more when combined with Loxapine. Make sure to check for potential interactions before prescribing using a tool like Rx Check.
Fun facts:
The brand formulation Loxitane is no longer on the market.
The inhalation powder formulation Adasuve was recently FDA approved.
Loxapine has structural similarities to Clozapine.
The prevalence of schizophrenia and related psychotic disorders in the U.S. is estimated between 0.25% and 0.64%.
Schizophrenia is one of the top 15 leading causes of disability worldwide.
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